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Medchemexpress LLC Vasicine (hydrochloride) | 7174-27-8 | 98.6% | 224.69 | 5 MG
SDP

Supplier:  Medchemexpress LLC 5MGHYN1103A

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Vasicine hydrochloride is a quinazoline alkaloid isolated from *Justicia adhatoda*. It activates the PI3K/Akt signaling pathway, demonstrating antioxidant, anti-inflammatory, and antibacterial properties. In vitro studies show it inhibits H+/K+-ATPase, scavenges DPPH free radicals, reduces gastric acid secretion, and has anti-ulcer effects. In vivo, it improves cardiac function, inhibits myocardial cell apoptosis, and alleviates myocardial damage and inflammation.

  • Inhibits H+/K+-ATPase and scavenges DPPH free radicals
  • Reduces gastric acid secretion; provides anti-ulcer effects
  • Improves cardiac function and inhibits myocardial cell apoptosis
  • Alleviates myocardial necrosis, edema, and inflammatory cell infiltration
  • Reduces LDH and CK-MB levels
  • Increases LVSP and myocardial contractility
  • Lowers TNF-α and IL-6 levels
  • Increases SOD and GPx activities in myocardial tissue

Catalog No. 50-003-93438


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