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Medchemexpress LLC Vasicine (hydrochloride) | 7174-27-8 | 98.6% | 224.69 | 5 MG

Supplier: Medchemexpress LLC 5MGHYN1103A
Vasicine hydrochloride is a quinazoline alkaloid isolated from *Justicia adhatoda*. It activates the PI3K/Akt signaling pathway, demonstrating antioxidant, anti-inflammatory, and antibacterial properties. In vitro studies show it inhibits H+/K+-ATPase, scavenges DPPH free radicals, reduces gastric acid secretion, and has anti-ulcer effects. In vivo, it improves cardiac function, inhibits myocardial cell apoptosis, and alleviates myocardial damage and inflammation.
- Inhibits H+/K+-ATPase and scavenges DPPH free radicals
- Reduces gastric acid secretion; provides anti-ulcer effects
- Improves cardiac function and inhibits myocardial cell apoptosis
- Alleviates myocardial necrosis, edema, and inflammatory cell infiltration
- Reduces LDH and CK-MB levels
- Increases LVSP and myocardial contractility
- Lowers TNF-α and IL-6 levels
- Increases SOD and GPx activities in myocardial tissue
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