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AdipoGen VASP human pAb
Supplier: AdipoGen AG25T0112R100
Polyclonal Antibody. Recognizes both the 46kDa Ser157 dephospho- and 50kDa Ser157 phospho- form of human VASP. Does not cross-react with mouse or rat VASP. Source Rabbit. Applications ICC, IP, WB. Liquid. Crude serum containing 0.02% sodium azide. VASP vasodilator-stimulated phosphoprotein is a proline-rich protein substrate of cAMP- and cGMP-dependent protein kinases. VASP is an actin-associated protein involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. VASP promotes actin filament elongation. It protects the barbed end of growing actin filaments against capping and increases the rate of actin polymerization in the presence of capping proteins.
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