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AdipoGen VASP mAb IE273
Supplier: AdipoGen AG20T0002C050
Monoclonal Antibody. Recognizes both the 46kDa Ser157 dephospho- and 50kDa Ser157 phospho- form of human, porcine, bovine, sheep and rabbit VASP. Isotype Mouse IgG1. Clone IE273. Applications ELISA, ICC, IHC, IP, WB. Liquid. In PBS containing 2mg/ml BSA and 0.02% sodium azide. VASP vasodilator-stimulated phosphoprotein is a proline-rich protein substrate of cAMP- and cGMP-dependent protein kinases. VASP is an actin-associated protein involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. VASP promotes actin filament elongation. It protects the barbed end of growing actin filaments against capping and increases the rate of actin polymerization in the presence of capping proteins.
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