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Medchemexpress LLC VE-821 | 1232410-49-9 | 99.7% | 368.41 | 10 MM 1 ML
SDP

Supplier:  Medchemexpress LLC HY1473110MM/1ML

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VE-821 is a potent ATP-competitive inhibitor of ATR with a Ki/IC50 of 13 nM/26 nM. It exhibits excellent selectivity for ATR with minimal cross-reactivity against related PIKKs. This compound significantly enhances the sensitivity of pancreatic cancer cells to radiation and Gemcitabine, making it suitable for studies on DNA damage response and cancer therapy.

  • Potent ATP-competitive inhibitor of ATR.
  • Exhibits excellent selectivity for ATR.
  • Enhances sensitivity of pancreatic cancer cells to radiation and Gemcitabine.
  • Inhibits radiation-induced G2/M arrest in cancer cells.
  • Soluble in DMSO (50 mg/mL).

Catalog No. 50-003-59999


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