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Genscript Corporation Antibody Protein Proteins Proteins 50 UG 1/EA
Supplier: Genscript Corporation Z0300650
Vascular Endothelial Growth Factor A164 (VEGF-A164) a member of the cysteine knot growth factor is one of major isoforms of VEGF-As. VEGF-As are endothelial cell-specific mitogens with angiogenic and vascular permeability-inducing properties. During maturation rat VEGF-A is alternatively spliced to generate rVEGF-A120 rVEGF-A164 and rVEGF-A188 which correspond to hVEGF-A121 hVEGF-A165 and hVEGF-A189 in human respectively (the numbers designate the amino acid residues). The active form of rVEGF-A164 is either a homodimeric or heterodimeric polypeptides which bind to the transmembrane tyrosine kinases receptors FLT1 FLK1 or KDR or to the non-tyrosine kinase neuropilin receptors NRP1/2.
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