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Apexbio Technology LLC Verbascoside 61276-17-3 10mg
Supplier: Apexbio Technology LLC B337910
Verbascoside (CAS 61276-17-3) is a small-molecule inhibitor targeting protein kinase C (PKC) and the NF- B signaling pathway It is designed to modulate these pathways thereby regulating signal transduction and transcriptional activity in cellular responses Verbascoside exerts its biological activity primarily through the inhibition of PKC and suppression of NF- B DNA-binding activation In cell-based studies Verbascoside demonstrates inhibitory activity with an IC50 value of approximately 4 8 M in RANKL-treated RAW264 7 cells and bone marrow macrophages (BMMs) Based on these pharmacological properties Verbascoside holds research potential in the investigation of PKC/NF- B-mediated signaling osteoclastogenesis and related cell signaling mechanisms
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