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Medchemexpress LLC Verteporfin | 129497-78-5 | 98.2% | 200 MG
Supplier: Medchemexpress LLC HYB0146200MG
Verteporfin (CL 318952) is a photosensitizer used in photodynamic therapy to eliminate abnormal blood vessels in the eye, especially those associated with age-related macular degeneration. It functions as a YAP inhibitor by disrupting YAP-TEAD interactions, inducing cell apoptosis. This compound also acts as an autophagy inhibitor, blocking autophagosome formation at an early stage.
- Acts as a YAP inhibitor, disrupting YAP-TEAD interactions.
- Induces cell apoptosis.
- Inhibits autophagy by blocking autophagosome formation at an early stage.
- Utilized as a photosensitizer for photodynamic therapy.
- Shows light-independent anti-leukemic activity.
- Reduces mitochondrial membrane potential in PDX cells.
- Reverses certain drug resistances by inhibiting YAP expression.
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