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Apexbio Technology LLC Vidarabine 5536-17-4 10mM (in 1mL DMSO)
Supplier: Apexbio Technology LLC B20625.1
Vidarabine is an antiviral nucleoside analog widely studied for inhibiting replication of herpes simplex virus (HSV) and varicella-zoster virus (VZV) Structurally vidarabine is an adenine arabinoside analog that interferes with viral DNA synthesis via competitive inhibition of viral DNA polymerase resulting in chain termination In vitro studies demonstrate antiviral activity against HSV type 1 and type 2 with IC50 values typically ranging approximately from 0 1 to 1 0 M depending on experimental conditions and viral strains Vidarabine is commonly used in biomedical laboratories for investigating viral replication mechanisms screening for antiviral candidates and elucidating nucleoside analog resistance patterns
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