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Medchemexpress LLC Vimirogant hydrochloride | 1802678-42-7 | 98.4% | C27H35F3N4O3S·XHCl | 10 MG
SDP

Catalog No. 5000244706
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Potent, selective RORγt inhibitor supplied as the hydrochloride salt for research use. It demonstrates low-nanomolar biochemical potency and cellular activity against IL-17A secretion and Th17 differentiation.

  • Potent RORγt inhibition (Ki = 3.5 nM; IC50 = 17 nM).
  • Reduces IL-17A secretion in human PBMCs (IC50 = 18 nM) and human whole blood (IC50 = 192 nM).
  • Inhibits Th17 differentiation in mouse splenocytes (IC50 = 57 nM).
  • High purity (98.4% by HPLC).
  • Available in small research pack sizes, e.g., 10 MG.

Catalog No. 50-002-44706 Supplier Medchemexpress LLC Supplier No. HY103637A10MG
May include imposed supplier surcharges.
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Potent, selective RORγt inhibitor supplied as the hydrochloride salt for research use. It demonstrates low-nanomolar biochemical potency and cellular activity against IL-17A secretion and Th17 differentiation.

  • Potent RORγt inhibition (Ki = 3.5 nM; IC50 = 17 nM).
  • Reduces IL-17A secretion in human PBMCs (IC50 = 18 nM) and human whole blood (IC50 = 192 nM).
  • Inhibits Th17 differentiation in mouse splenocytes (IC50 = 57 nM).
  • High purity (98.4% by HPLC).
  • Available in small research pack sizes, e.g., 10 MG.

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