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Medchemexpress LLC Vinblastine sulfate | 143-67-9 | 99.56% | 909.05 | 25 MG
SDP

Supplier:  Medchemexpress LLC 25MGHY13780R

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Vinblastine sulfate is a cytotoxic alkaloid effective against various cancer types. It inhibits microtubule formation and suppresses nAChR with an IC50 of 8.9 μM. It blocks mitosis and induces apoptosis by altering p53 and causing DNA fragmentation, leading to an antiproliferative effect via Bax/Bcl-2 imbalance.

  • Inhibits microtubule formation
  • Suppresses nAChR activity
  • Blocks mitosis and induces apoptosis
  • Exhibits antiproliferative effects via Bax/Bcl-2 imbalance
  • Modulates NFκB and JNK pathways
  • Triggers apoptosis through mitochondrial pathway
  • Targets Microtubule/Tubulin, Autophagy, and nAChR
  • Involved in Cell Cycle/DNA Damage and Cytoskeleton pathways
  • Soluble in water (50 mg/mL) and DMSO (≥ 44 mg/mL)
  • Intended for research use only

Catalog No. 50-003-49816


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