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Apexbio Technology LLC Vinblastine sulfate 143-67-9 50mg
Supplier: Apexbio Technology LLC A392050
Vinblastine sulfate (CAS 143-67-9) is a bioactive small molecule that exerts antitumor effects primarily by disrupting microtubule formation a critical process for cell division Additionally vinblastine inhibits neuronal nicotinic acetylcholine receptor (nAChR) activity exhibiting an IC50 of 8 9 M In vitro studies demonstrated cytotoxicity with EC50 values around 15 g/mL against P815 mastocytoma cells Clinical research continues to explore vinblastine sulfate both as a monotherapy and within chemotherapeutic combinations investigating treatment protocols for metastatic melanoma and other cancers
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