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Apexbio Technology LLC Vincristine sulfate 2068-78-2 100mg
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Supplier:  Apexbio Technology LLC A1765100

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Vincristine sulfate (CAS 2068-78-2) is a natural alkaloid isolated from the leaves of Catharanthus roseus structurally composed of two heterocyclic monomers vindoline and catharanthine connected by a bridging carbon It acts via inhibition of microtubule polymerization binding tubulin with a Ki of approximately 0 085 M In vitro vincristine demonstrates antiproliferative activity against B16 melanoma cells with an IC50 of 0 45 M The compound exhibits promising activity in research settings targeting diverse cancers including acute lymphoblastic leukemia acute non-lymphoblastic leukemia non-Hodgkin lymphoma Hodgkin disease and brain tumors

Catalog No. 50-000-63095


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