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Medchemexpress LLC Vincristine sulfate | 2068-78-2 | 923.04 | 100 MG

Supplier: Medchemexpress LLC HYN0488100MG
Vincristine sulfate is an antitumor vinca alkaloid that inhibits microtubule formation in the mitotic spindle, leading to an arrest of dividing cells at the metaphase stage. It binds to microtubules with a Ki of 85 nM.
- Inhibits microtubule formation in the mitotic spindle.
- Leads to an arrest of dividing cells at the metaphase stage.
- Binds to microtubules with a Ki of 85 nM.
- Induces apoptosis in tumor cells.
- Inhibits SH-SY5Y cell proliferation.
- Induces mitotic arrest and promotes expression of caspase-3 and -9 and cyclin B.
- Decreases cyclin D expression.
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