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Medchemexpress LLC Vincristine sulfate | 2068-78-2 | 923.04 | 5 MG
SDP

Supplier:  Medchemexpress LLC HYN04885MG

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Vincristine sulfate is an antitumor vinca alkaloid that inhibits microtubule formation in mitotic spindle, leading to an arrest of dividing cells at the metaphase stage. It binds to microtubule with a Ki of 85 nM.

  • Antitumor vinca alkaloid
  • Inhibits microtubule formation in mitotic spindle
  • Results in arrest of dividing cells at the metaphase stage
  • Binds to microtubule with a Ki of 85 nM
  • Induces apoptosis in tumor cells
  • Inhibits SH-SY5Y cell proliferation with IC50 of 0.1 μM
  • Induces mitotic arrest and promotes expression of caspase-3 and -9 and cyclin B, while decreasing expression of cyclin D

Catalog No. 50-003-90232


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