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Enzo Life Sciences Vincristine. sulfate (25 mg). CAS: 2068-78-2
Supplier: Enzo Life Sciences BMLT1170025
Plant alkaloid that arrests the cell cycle in G2/M phase by blocking mitotic spindle formation. Depolymerizes microtubules and blocks binding of tubulin to microtubule proteins. Causes aberrant tubulin polymerization. Induces apoptosis. Triggers Raf-1 activation, phosphorylation of Bcl-2 family proteins and induction of p53 expression. Cancer chemotherapeutic agent. Posttranscriptionally downregulates HIF-1α expression. Alternative name: VCR . sulfate, Leukocristine . sulfate. Purity: ≥98% TLC. Solubility: Soluble in water (25mg/ml) or methanol. Long Term Storage: -20°C.
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