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Cayman Chemical VItamIn K3-d8 50mg
SDP

Supplier:  Cayman Chemical 4128550 MG

Encompass_Preferred

An inhibitor of NOTUM (IC50 6.7 nM) selective for NOTUM over a panel of 39 serine hydrolases and 485 kinases including CK1 and GSK3 at 10 UM and a panel of 47 receptors ion channels transporters and enzymes at 30 UM but does inhibit 5-HT3A a4B2 subunit-containing nAChRs and MAO-A (IC50s 4.5 10 and 28 UM respectively) prevents NOTUM-induced decreases in Wnt3a signaling in a cell-based reporter assay (EC50 110 nM)

Catalog No. 50-294-4258


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