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Medchemexpress LLC Vitamin K4 | 573-20-6 | 99.9% | 1 G
Supplier: Medchemexpress LLC HYB15081G
Vitamin K4 is a chemically synthesized Vitamin K that plays an important role in the normal blood coagulation system. It arrests cells in the S phase of the cell cycle and induces apoptosis, and can be used for research on cancer, including prostate cancer and osteosarcoma.
- Inhibits cell proliferation and induces caspase-dependent apoptosis in PC-3 cells.
- Induces S phase cell cycle arrest in PC-3 and U2OS cells.
- Inhibits the growth of U2OS cells.
- Increases ROS generation and disrupts mitochondrial membrane potential in U2OS cells.
- Inhibits the migration of U2OS cells in vitro.
- Modulates expression of Bcl-2, Bax, PARP, and cleaved-caspase-3.
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