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Medchemexpress LLC VK-II-86 | 955371-84-3 | 93.3% | 420.50 | 500 MG
Supplier: Medchemexpress LLC HY1110131MG
VK-II-86 is a Carvedilol analogue that lacks antagonist activity at β-adrenoceptors in hypokalaemia. This compound effectively prevents hypokalaemia-induced ventricular arrhythmia through its multi-channel effects, counteracting all hypokalaemia-induced changes in ion channel activity and oxidative stress. For research use only.
- Carvedilol analogue
- Lacks antagonist activity at β-adrenoceptors
- Prevents hypokalaemia-induced ventricular arrhythmia
- Exhibits multi-channel effects
- Counters hypokalaemia-induced changes in ion channel activity
- Counters hypokalaemia-induced oxidative stress
- Markedly reduces non-sustained and sustained ventricular tachyarrhythmias in a hypokalaemic murine whole-heart model
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