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Medchemexpress LLC Vk-II-86 (carvedilol analogue) | 955371-84-3 | 93.3% | 420.50 | C25H28N2O4 | 5 MG
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Supplier:  Medchemexpress LLC HY1110135MG

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VK-II-86 is a carvedilol analogue and a store-overload-induced calcium release (SOICR) inhibitor used as a research chemical to study cardiac arrhythmia mechanisms and calcium homeostasis. It lacks β-adrenoceptor antagonist activity and has been shown to prevent hypokalaemia-induced ventricular arrhythmia by normalizing ion channel activity and repolarization reserve.

  • Inhibits store-overload-induced calcium release, supporting arrhythmia research.
  • Lacks β-adrenoceptor antagonist activity, reducing β-blocking confounds in studies.
  • Reported to normalize calcium homeostasis and repolarization reserve in models.
  • Solid, light brown to brown appearance and supplied in small milligram quantities.
  • Molecular weight 420.50 g/mol; formula C25H28N2O4.
  • High purity (93.3%) suitable for laboratory research applications.

Catalog No. 50-002-63631


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