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Medchemexpress LLC Voacamine | 3371-85-5 | 10 MG
SDP

Supplier:  Medchemexpress LLC HYN693210MG

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Voacamine is an indole alkaloid with cannabinoid 1 (CB1) antagonistic activity. It inhibits nuclear translocation and enhances the effect of Doxorubicin by interfering with P-glycoprotein (P-gp) function. It promotes apoptosis-independent autophagic cell death in human osteosarcoma cells, activates the mitochondrial-associated apoptosis signaling pathway, and inhibits the PI3K/Akt/mTOR signaling pathway to suppress breast cancer progression. Voacamine also inhibits EGFR to exert oncogenic activity against colorectal cancer.

  • High purity of 99.64%
  • Inhibits nuclear translocation
  • Enhances Doxorubicin efficacy by interfering with P-gp function
  • Promotes apoptosis-independent autophagic cell death
  • Suppresses breast cancer progression via PI3K/Akt/mTOR pathway inhibition
  • Exerts oncogenic activity against colorectal cancer by inhibiting EGFR

Catalog No. 50-004-18473


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