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Cell Signaling Technology Vorinostat (SAHA), HDAC Inhibitor, >99% Purity, 5 mg
SDP

Catalog No. 502050458
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Vorinostat (SAHA) is a histone deacetylase (HDAC) inhibitor that functions by binding to and blocking the active site of the enzyme. It inhibits both class I and class II HDACs at nanomolar concentrations, leading to the accumulation of acetylated histones and other proteins that regulate gene expression. This activity can induce cell cycle arrest, differentiation, or apoptosis in transformed cell types.

  • Inhibits class I and class II HDACs
  • Induces cell cycle arrest and apoptosis
  • Supplied as a lyophilized powder
  • Purity >99%
  • Molecular weight 264.32 g/mol
  • Soluble in DMSO at 66 mg/mL and ethanol at 2 mg/mL

Catalog No. 50-205-0458 Supplier Cell Signaling Technology Supplier No. 12520S
May include imposed supplier surcharges.
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Vorinostat (SAHA) is a histone deacetylase (HDAC) inhibitor that functions by binding to and blocking the active site of the enzyme. It inhibits both class I and class II HDACs at nanomolar concentrations, leading to the accumulation of acetylated histones and other proteins that regulate gene expression. This activity can induce cell cycle arrest, differentiation, or apoptosis in transformed cell types.

  • Inhibits class I and class II HDACs
  • Induces cell cycle arrest and apoptosis
  • Supplied as a lyophilized powder
  • Purity >99%
  • Molecular weight 264.32 g/mol
  • Soluble in DMSO at 66 mg/mL and ethanol at 2 mg/mL

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