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Medchemexpress LLC Vortioxetine | 508233-74-7 | C18H22N2S | 500 MG
SDP

Catalog No. 5000376532
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Vortioxetine (Lu AA 21004) is an antagonist of 5-HT3A and 5-HT7 receptors (Ki: 3.7 nM, 19 nM) and an inhibitor of serotonin transporter (SERT) (Ki: 1.6 nM). It also acts as a 5-HT1A agonist and a partial agonist of 5-HT1B (Ki: 15 nM, 33 nM).

  • Antagonistic properties at 5-HT3A and 5-HT7 receptors.
  • Partial agonist properties at 5-HT1B receptors.
  • Agonistic properties at 5-HT1A receptors.
  • Potent inhibition of SERT.
  • Significantly increases cell proliferation and cell survival, and stimulates maturation of immature granule cells in the sub granular zone of the dentate gyrus of the hippocampus after 21 days of treatment.
  • Does not cause cognitive or psychomotor impairment.

Catalog No. 50-003-76532 Supplier Medchemexpress LLC Supplier No. HY15414500MG
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Vortioxetine (Lu AA 21004) is an antagonist of 5-HT3A and 5-HT7 receptors (Ki: 3.7 nM, 19 nM) and an inhibitor of serotonin transporter (SERT) (Ki: 1.6 nM). It also acts as a 5-HT1A agonist and a partial agonist of 5-HT1B (Ki: 15 nM, 33 nM).

  • Antagonistic properties at 5-HT3A and 5-HT7 receptors.
  • Partial agonist properties at 5-HT1B receptors.
  • Agonistic properties at 5-HT1A receptors.
  • Potent inhibition of SERT.
  • Significantly increases cell proliferation and cell survival, and stimulates maturation of immature granule cells in the sub granular zone of the dentate gyrus of the hippocampus after 21 days of treatment.
  • Does not cause cognitive or psychomotor impairment.

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