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Medchemexpress LLC Vortioxetine (hydrobromide) | 960203-27-4 | C18H23BrN2S | 200 MG
Supplier: Medchemexpress LLC HY15414A200MG
Vortioxetine (Lu AA 21004) hydrobromide is an antagonist of 5-HT3A and 5-HT7 receptors (Ki: 3.7 nM, 19 nM) and an inhibitor of 5-hydroxytryptamine transporter (SERT) (Ki: 1.6 nM). It also acts as a 5-HT1A agonist and a partial 5-HT1B agonist (Ki: 15 nM, 33 nM).
- Multimodal serotonergic agent.
- Displays antagonistic properties at 5-HT3A and 5-HT7 receptors.
- Exhibits partial agonist properties at 5-HT1B receptors.
- Shows agonistic properties at 5-HT1A receptors.
- Potent inhibition of SERT.
- Increases cell proliferation and cell survival, and stimulates maturation of immature granule cells in the dentate gyrus of the hippocampus.
- Does not cause cognitive or psychomotor impairment.
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