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Medchemexpress LLC VPC-70619 | 2361742-30-3 | 99.93% | C16H8ClF3N4O | 100 MG
Supplier: Medchemexpress LLC HY144878100MG
VPC-70619 is a potent N-Myc inhibitor that blocks the binding of the N-Myc-Max heterocomplex to the DNA E-box and shows strong inhibitory activity against N-Myc-dependent cell lines. It can partially reverse paclitaxel resistance in cells by reducing MYCN expression and can be used for cancer research, including neuroblastoma and thyroid cancer.
- Potent N-Myc inhibitor
- Blocks the binding of the N-Myc-Max heterocomplex to the DNA E-box
- Shows strong inhibitory activity against N-Myc-dependent cell lines
- Partially reverses paclitaxel resistance by reducing MYCN expression
- Can be used for cancer research, including neuroblastoma and thyroid cancer
- Demonstrates high inhibition rates in certain cell types
- Highly stable in liver microsomes
- Regulates MYCN signaling pathway
- Inhibits proliferation, migration, and aggressiveness of cancer cells
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