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Medchemexpress LLC Vps34-PIK-III | 1383716-40-2 | 99.6% | 1 ML
SDP

Supplier:  Medchemexpress LLC HY1279410MM/1ML

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Vps34-PIK-III is an orally active and selective VPS34 inhibitor (IC50=18 nM) that effectively inhibits autophagy and can be used as a molecular tool. It is also a PI3K inhibitor that inhibits the expression of genes in liver cancer stem cells (CSCs).

  • Orally active and selective VPS34 inhibitor (IC50=18 nM).
  • Effectively inhibits autophagy.
  • Can serve as a molecular tool.
  • PI3K inhibitor.
  • Suppresses the expression of genes in liver cancer stem cells.
  • Inhibits autophagy and LC3 lipidation in DLD1 cells.
  • Decreases the expression of stemness genes in HCC cells.
  • Suppresses liver CSCs via AMPK activation in Huh7 and MHCC97H cells.

Catalog No. 50-003-42156


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