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Medchemexpress LLC VRT-534 | 926664-32-6 | 98.3% | 497.99 | 5 MG
SDP

Catalog No. 5000361046
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VRT-534 is a chemical chaperone (Compound 3) that targets connexin 26 (Cx26), demonstrating dose-responsive binding to recombinant wild-type Cx26 and mutant Cx26 K188N with EC50s of 19 and 5 μM, respectively. It is useful in research concerning hearing impairment. In vitro studies indicate that VRT-534 (50 μM; 24h) restores the vitality of HeLa cells and shows restorative effects on Cx26 mutants L90P and F161S in HeLa cells.

  • Targets connexin 26 (Cx26)
  • Exhibits dose-responsive binding to recombinant wild-type Cx26 and mutant Cx26 K188N
  • Useful in research related to hearing impairment
  • Restores vitality of HeLa cells
  • Shows restorative effect on Cx26 mutants L90P and F161S in HeLa cells

Catalog No. 50-003-61046 Supplier Medchemexpress LLC Supplier No. HY1493185MG
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VRT-534 is a chemical chaperone (Compound 3) that targets connexin 26 (Cx26), demonstrating dose-responsive binding to recombinant wild-type Cx26 and mutant Cx26 K188N with EC50s of 19 and 5 μM, respectively. It is useful in research concerning hearing impairment. In vitro studies indicate that VRT-534 (50 μM; 24h) restores the vitality of HeLa cells and shows restorative effects on Cx26 mutants L90P and F161S in HeLa cells.

  • Targets connexin 26 (Cx26)
  • Exhibits dose-responsive binding to recombinant wild-type Cx26 and mutant Cx26 K188N
  • Useful in research related to hearing impairment
  • Restores vitality of HeLa cells
  • Shows restorative effect on Cx26 mutants L90P and F161S in HeLa cells

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