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Medchemexpress LLC VU 0357121 | 433967-28-3 | C17H17F2NO2 | 1 ML
SDP

Supplier:  Medchemexpress LLC HY1539310MM/1ML

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VU 0357121 is a positive and highly selective mGlu5R allosteric modulator (PAM) with an EC50 of 33 nM. It is inactive or very weakly antagonizing at other mGlu receptor subtypes.

  • Positive and highly selective mGlu5R allosteric modulator (PAM)
  • EC50 of 33 nM for mGlu5 receptor
  • Inactive or very weakly antagonizing at other mGlu receptor subtypes
  • Enhances glutamate sensitivity of mGlu5
  • Does not bind at the MPEP allosteric site of mGlu5
  • For research use only

Catalog No. 50-003-76261


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