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Medchemexpress LLC VU 0364439 | 1246086-78-1 | C18H13Cl2N3O3S | 100 MG
SDP

Supplier:  Medchemexpress LLC HY15476100MG

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VU 0364439 is a mGlu4 positive allosteric modulator (PAM) with an EC50 of 19.8 nM. While it exhibits less than ideal PK properties for in vivo use, it demonstrates better stability in HLM (63% remaining) compared to RLM (2% remaining).

  • mGlu4 positive allosteric modulator
  • Exhibits an EC50 of 19.8 nM
  • Shows improved stability in HLM (63% remaining) compared to RLM (2% remaining)
  • Soluble in DMSO (50 mg/mL)
  • Targets mGluR in GPCR/G Protein and neuronal signaling pathways

Catalog No. 50-003-76217


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