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Medchemexpress LLC VU 0364439 | 1246086-78-1 | C18H13Cl2N3O3S | 5 MG

Supplier: Medchemexpress LLC HY154765MG
VU 0364439 is a mGlu4 positive allosteric modulator (PAM) with an EC50 of 19.8 nM. It exhibits better stability in HLM (63% remaining) than RLM (2% remaining), though it possesses less than ideal pharmacokinetic properties preventing its use as an in vivo tool.
- mGlu4 positive allosteric modulator (PAM)
- EC50 of 19.8 nM for mGlu4 Receptor
- High purity of 99.42%
- White to off-white solid appearance
- Demonstrates positive allosteric modulation of human mGlu4 receptor in CHO cells
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