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Medchemexpress LLC VU 0364439 | 1246086-78-1 | C18H13Cl2N3O3S | 50 MG

Supplier: Medchemexpress LLC HY1547650MG
VU 0364439 is a mGlu4 positive allosteric modulator (PAM), with an EC50 of 19.8 nM. Intended for research use only, this solid compound appears white to off-white. While it demonstrates better stability in Human Liver Microsomes, its less than ideal PK properties prevent its use as an in vivo tool.
- Positive allosteric modulator (PAM) for mGlu4
- EC50 of 19.8 nM
- Purity of 99.42%
- Solid appearance, white to off-white color
- Exhibits better stability in HLM (63% remaining) compared to RLM (2% remaining)
- Target: mGluR
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