Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Medchemexpress LLC VU-1545 | 890764-63-3 | 99.0% | 402.38 | 25 MG
Supplier: Medchemexpress LLC 25MGHY16951
VU-1545 is a potent metabotropic glutamate receptor 5 (mGluR5) positive allosteric modulator (PAM) with a Ki of 156 nM and an EC50 of 9.6 nM. It promotes AKT activation, efficiently doing so at concentrations as low as 0.1 and 1.0 μM. Studies have shown that VU-1545 at 10 and 100 μM promotes Akt phosphorylation. This compound is used for research purposes and is not intended for patient use.
- Potent mGluR5 positive allosteric modulator
- Ki of 156 nM for mGluR5
- EC50 of 9.6 nM for mGluR5
- Promotes AKT activation in neuronal cells
- Efficiently promotes Akt phosphorylation at 10.0 μM and 100.0 μM
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?