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Medchemexpress LLC VU0155041 | 1093757-42-6 | 99.10% | C14H15Cl2NO3 | 100 MG
Supplier: Medchemexpress LLC HY14417100MG
VU0155041 is a potent and selective positive allosteric modulator (PAM) of mGluR4, with EC50s of 798 nM for human mGluR4 and 693 nM for rat mGluR4. It has potential for the research of Parkinson's disease (PD).
- Potent, selective positive allosteric modulator (PAM) of mGluR4
- EC50s of 798 nM (human mGluR4) and 693 nM (rat mGluR4)
- Does not affect NMDA receptor currents in striatal medium spiny neurons
- Reverses catalepsy induced by Haloperidol in rats
- Reverses Reserpine-induced akinesia in rats
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