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Medchemexpress LLC Vu0155041 | 1093757-42-6 | 99.10% | C14H15Cl2NO3 | 50 MG
Supplier: Medchemexpress LLC HY1441750MG
VU0155041 is a potent, selective positive allosteric modulator (PAM) of mGluR4, with EC50s of 798 nM and 693 nM for human and rat mGluR4, respectively. VU0155041 has potential for the research of Parkinson's disease (PD).
- Potent and selective positive allosteric modulator (PAM) of mGluR4
- EC50s of 798 nM for human mGluR4
- EC50s of 693 nM for rat mGluR4
- Potential for Parkinson's disease research
- Does not affect NMDA receptor currents in striatal medium spiny neurons at 10 μM in vitro
- Reverses catalepsy induced by dopamine D2 receptor antagonist Haloperidol in rats
- Reverses Reserpine-induced akinesia in rats
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