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Cayman Chemical VU0155041sodIum salt 50mg
SDP

Catalog No. 502986605
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A selective positive allosteric modulator of mGluR4 (EC50 = 2.5 μM in a thallium flux assay); has no effect on radioligand binding at 67 G protein-coupled receptors, ion channels, and transporters; lacks antagonist activity at NMDA receptors in striatal medium spiny neurons at a concentration of 10 μM; decreases haloperidol-induced catalepsy and reverses reserpine-induced askinesias in rat models of Parkinson’s disease; restores social behavior in the Oprm-/- mouse model of autism; decreases anxiety-like behavior in the elevated plus maze in mice

Catalog No. 50-298-6605 Supplier Cayman Chemical Supplier No. 2177550 MG
May include imposed supplier surcharges.
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A selective positive allosteric modulator of mGluR4 (EC50 = 2.5 μM in a thallium flux assay); has no effect on radioligand binding at 67 G protein-coupled receptors, ion channels, and transporters; lacks antagonist activity at NMDA receptors in striatal medium spiny neurons at a concentration of 10 μM; decreases haloperidol-induced catalepsy and reverses reserpine-induced askinesias in rat models of Parkinson’s disease; restores social behavior in the Oprm-/- mouse model of autism; decreases anxiety-like behavior in the elevated plus maze in mice

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