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Medchemexpress LLC VU0463271 | 1391737-01-1 | 99.8% | 382.50 | 1 ML

Supplier: Medchemexpress LLC HY110110100MG
VU0463271 is a selective KCC2 antagonist, with an IC50 of 61 nM. It offers a potent and selective antagonist activity, making it suitable for various research applications.
- Selective KCC2 antagonist
- IC50 of 61 nM (KCC2)
- Greater than 100-fold selectivity versus the closely related Na-K-2Cl cotransporter 1 (NKCC1)
- No activity in a larger panel of GPCRs, ion channels, and transporters
- Rapidly cleared in vitro
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