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Medchemexpress LLC VU0810464 | 2126040-21-7 | 99.3% | 50 MG
SDP

Catalog No. 5000341703
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VU0810464 is a potent and selective non-urea G protein-gated inwardly-rectifying potassium channels (GIRK, Kir3) activator. It demonstrates nanomolar potency for neuronal (EC50=165 nM) and GIRK1/4 (EC50=720 nM) channels. It exhibits improved brain penetration and reduces stress-induced hyperthermia (SIH) in mice by activating Kir3 channels.

  • Potent and selective activator of GIRK (Kir3) channels
  • Displays nanomolar potency for neuronal and GIRK1/4 channels
  • Exhibits improved brain penetration
  • Reduces stress-induced hyperthermia (SIH) in mice

Catalog No. 50-003-41703 Supplier Medchemexpress LLC Supplier No. HY12710650MG
May include imposed supplier surcharges.
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VU0810464 is a potent and selective non-urea G protein-gated inwardly-rectifying potassium channels (GIRK, Kir3) activator. It demonstrates nanomolar potency for neuronal (EC50=165 nM) and GIRK1/4 (EC50=720 nM) channels. It exhibits improved brain penetration and reduces stress-induced hyperthermia (SIH) in mice by activating Kir3 channels.

  • Potent and selective activator of GIRK (Kir3) channels
  • Displays nanomolar potency for neuronal and GIRK1/4 channels
  • Exhibits improved brain penetration
  • Reduces stress-induced hyperthermia (SIH) in mice

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