Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 502240189

Apexbio Technology LLC WAY 316606(Synonyms: WAY-316606, WAY316606, WAY 316606 sFRP-1 inhibitor, sFRP-1 inhibitor WAY 316606), 5mg, CAS: 915759-45-4.
SDP

Catalog No. 502240189
Encompass_Preferred

WAY 316606 (CAS 915759-45-4) is a selective small molecule inhibitor targeting secreted frizzled-related protein 1 (sFRP-1) an endogenous antagonist of Wnt signaling WAY 316606 binds specifically to sFRP-1 (Kd 0 08 M) reducing its inhibitory effect and thus activating the canonical Wnt pathway In cell-based reporter assays using U2-OS osteosarcoma cells WAY 316606 dose-dependently promoted Wnt signaling with an EC50 of 0 65 M Ex vivo studies with neonatal murine calvarial tissue further demonstrated that WAY 316606 enhances osteoblast activity and bone formation This compound serves as a research tool for investigating Wnt-associated bone metabolism and therapeutic strategies for metabolic bone disorders

This item is not returnable. View return policy
Catalog No. 50-224-0189 Supplier Apexbio Technology LLC Supplier No. A39325
May include imposed supplier surcharges.
Add to Cart
Add to Cart

missing translation for 'validMainframeMsg'

WAY 316606 (CAS 915759-45-4) is a selective small molecule inhibitor targeting secreted frizzled-related protein 1 (sFRP-1) an endogenous antagonist of Wnt signaling WAY 316606 binds specifically to sFRP-1 (Kd 0 08 M) reducing its inhibitory effect and thus activating the canonical Wnt pathway In cell-based reporter assays using U2-OS osteosarcoma cells WAY 316606 dose-dependently promoted Wnt signaling with an EC50 of 0 65 M Ex vivo studies with neonatal murine calvarial tissue further demonstrated that WAY 316606 enhances osteoblast activity and bone formation This compound serves as a research tool for investigating Wnt-associated bone metabolism and therapeutic strategies for metabolic bone disorders

This item is not returnable. View return policy
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.