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AdipoGen Wedelolactone

Supplier: AdipoGen AGCN20424M001
Chemical. CAS 524-12-9. Formula C16H10O7. MW 314.2. Isolated from Eclipta prostrata. Cell permeable, selective and irreversible IKKalpha and beta kinase activity inhibitor. NF-kappaB inhibitor. Blocks phosphorylation and degradation of IkappaBalpha. Antihepatotoxic. 5-Lipoxygenase 5-LOX inhibitor. Anti-inflammatory. HIV-1 integrase inhibitor. Anticancer and antiproliferative compound. Modulates androgen receptor AR activation. Apoptosis inducer via downregulation of PKCepsilon. DNA topoisomerase IIalpha inhibitor. G protein-coupled receptor-35 GPR35 agonist. Inhibits adipogenic differentiation of mesenchymal stem cells hAMSCs through ERK pathway. STAT1 protein dephosphorylation inhibitor. Antifibrotic.
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