Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000349585

Medchemexpress LLC WEE1-IN-3 | 2272976-28-8 | 98.6% | 497.59 | 100 MG
SDP

Catalog No. 5000349585
Encompass_Preferred

WEE1-IN-3 is a potent inhibitor of Wee1 kinase with an IC50 of less than 10 nM. It demonstrates anticancer activities. WEE1 kinase is crucial for the G2-M cell-cycle checkpoint, which is involved in DNA repair before mitotic entry. While normal cells repair damaged DNA during G1 arrest, cancer cells often have a deficient G1-S checkpoint and rely on a functional G2-M checkpoint for DNA repair. WEE1 is found to be overexpressed in various cancer types. WEE1-IN-3 inhibits cancer cell growth with IC50 values of 100-1000 nM for SW480 cells and less than 100 nM for H23 cells.

  • Potent Wee1 kinase inhibitor with an IC50 of <10 nM.
  • Exhibits anticancer activities.
  • Inhibits cancer cell growth in SW480 and H23 cells.
  • Available as solid or solution in DMSO.

Catalog No. 50-003-49585 Supplier Medchemexpress LLC Supplier No. HY138239100MG
May include imposed supplier surcharges.
Add to Cart
Add to Cart

WEE1-IN-3 is a potent inhibitor of Wee1 kinase with an IC50 of less than 10 nM. It demonstrates anticancer activities. WEE1 kinase is crucial for the G2-M cell-cycle checkpoint, which is involved in DNA repair before mitotic entry. While normal cells repair damaged DNA during G1 arrest, cancer cells often have a deficient G1-S checkpoint and rely on a functional G2-M checkpoint for DNA repair. WEE1 is found to be overexpressed in various cancer types. WEE1-IN-3 inhibits cancer cell growth with IC50 values of 100-1000 nM for SW480 cells and less than 100 nM for H23 cells.

  • Potent Wee1 kinase inhibitor with an IC50 of <10 nM.
  • Exhibits anticancer activities.
  • Inhibits cancer cell growth in SW480 and H23 cells.
  • Available as solid or solution in DMSO.

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.