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Medchemexpress LLC WEE1-IN-3 | 2272976-28-8 | 98.6% | 497.59 | 50 MG
SDP

Catalog No. 5000349431
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WEE1-IN-3 is a potent Wee1 kinase inhibitor, demonstrating an IC50 of less than 10 nM. This compound has shown anticancer activities by inhibiting cancer cell growth, with IC50 values ranging from 100-1000 nM for SW480 cells and under 100 nM for H23 cells. It targets Wee1 kinase, which is crucial for the G2-M cell-cycle checkpoint, a mechanism often exploited by cancer cells that have compromised G1-S checkpoints, and is frequently overexpressed in various cancer types.

  • Potent inhibition of Wee1 kinase.
  • Exhibits anticancer activities.
  • Inhibits the growth of cancer cells.
  • Targets the G2-M cell-cycle checkpoint.
  • Effective against cells with compromised G1-S checkpoints.

Catalog No. 50-003-49431 Supplier Medchemexpress LLC Supplier No. HY13823950MG
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WEE1-IN-3 is a potent Wee1 kinase inhibitor, demonstrating an IC50 of less than 10 nM. This compound has shown anticancer activities by inhibiting cancer cell growth, with IC50 values ranging from 100-1000 nM for SW480 cells and under 100 nM for H23 cells. It targets Wee1 kinase, which is crucial for the G2-M cell-cycle checkpoint, a mechanism often exploited by cancer cells that have compromised G1-S checkpoints, and is frequently overexpressed in various cancer types.

  • Potent inhibition of Wee1 kinase.
  • Exhibits anticancer activities.
  • Inhibits the growth of cancer cells.
  • Targets the G2-M cell-cycle checkpoint.
  • Effective against cells with compromised G1-S checkpoints.

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