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Cayman Chemical Werner Syndrome RecQ Helicase
Supplier: Cayman Chemical 416781 MG
An inhibitor of WRN (IC50 = 100 nM); selectively inhibits the growth of SW48 cells over DLD-1-WRN-KO cells (GI50s = 100 and >10,000 nM, respectively); reduces tumor volume in an SW48 mouse xenograft model at 120 mg/kg per day
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