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Cayman Chemical Werner Syndrome RecQ Helicase

Supplier: Cayman Chemical 416795 MG

An antagonist of yoda1-activated Piezo1 (IC50 1.3 UM in HEK293 cells expressing the human receptor) selective for yoda1-actived Piezo1 over constituitively active Piezo1 TRPV4 and TRPC4 at 10 UM reduces the percentage of cells with yoda1-induced extracellular phosphatidylserine exposure in RBCs isolated from patients with sickle cell anemia at 10 UM inhibits yoda1-induced relaxation of isolated mouse aortic rings at 10 UM
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