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Cayman Chemical Werner Syndrome RecQ Helicase

Supplier: Cayman Chemical 416795 MG
An inhibitor of WRN (IC50 = 60 nM); selectively inhibits the growth of SW48 cells over DLD-1-WRN-KO cells (GI50s = 70 and >10,000 nM, respectively); reduces tumor volume in an SW48 mouse xenograft model at 240 mg/kg per day
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