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Abcam Withaferin A from Withania somnifera, 1MG
Supplier: Abcam AB1206441MG
MW 470.6 g/mol, Purity >98%. Naturally occurring withanolide/steroidal lactone with anticancer properties. Demonstrates a number of cellular effects including the covalent binding to annexin II, inhibition of chymotrypsin-like activity, PKC and caspase 3. Causes translocation of cyctochrome C to the nucleous and the cleavage of PLC-γ1. Down-regulates Notch 1, 3, cdc25C, phosphorylated Akt and bcl-2 proteins.
The product is subject to the following: Abcam Restricted Use Statement
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