Medchemexpress LLC Wnt3a Surrogate Hum 100ug | 100ug

Supplier:  Medchemexpress LLC HYP70453C100UG

Wnt3a Surrogate protein is a Wnt recombination protein that plays an important role in embryonic development adult tissue homeostasis and injury repair Wnt3a Surrogate protein consisting of the domain and Fc portion of Wnt3a helps organoids expand and maintain a source of Wnt Organoids are a rapidly evolving model system for tissue development and Wnt3a is considered as the essential protein for organoid growth Wnt3a or the small molecule glycogen synthase kinase 3 (GSK3) inhibitor CHIR are commonly used as Wnt sources in experiments However the application of Wnt3a is hampered by Wnt lipidation and cross-reactivity with Wnt frizzled (Fzd) Therefore Wnt3a Surrogate protein was used instead of Wnt3a as a water-soluble and Fzd-specific alternative Wnt agonist And the Wnt3a Surrogate protein exhibits tissue selectivity consistent with Fzd isoform specificity[1][2][3] Wnt3a Surrogate Protein Human (HEK293 C-hFc) is the recombinant human-derived Wnt3a Surrogate

Catalog No. 50-001-84464