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Medchemexpress LLC WRW4 | 878557-55-2 | 99.8% | 1104.27 | 5 MG
SDP

Supplier:  Medchemexpress LLC HYP11195MG

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WRW4 is a specific formyl peptide receptor-like 1 (FPRL1) antagonist. It inhibits WKYMVm binding to FPRL1 with an IC50 of 0.23 μM. WRW4 specifically inhibits the increase in intracellular calcium by the FPRL1 agonists MMK-1, amyloid beta42 (Abeta42) peptide, and F peptide.

  • Specifically inhibits FPRL1, a receptor involved in various cellular processes.
  • Inhibits Abeta42 peptide-induced superoxide generation and chemotactic migration of neutrophils.
  • Completely inhibits the internalization of Abeta42 peptide in human macrophages.
  • Blocks ERK phosphorylation downstream of FPRL1, which is induced by WKYMVm.

Catalog No. 50-004-24037


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