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CPC Scientific H-Trp-Arg-Trp-Trp-Trp-Trp-OH (trifluoroacetate salt) 1MG
Supplier: CPC Scientific SIGN018A
This peptide inhibits binding of one of formyl peptide receptor-like 1 (FPRL1) agonists WKYMVm to its specific receptor. FPRL1 is an important classical chemoattractant receptor that is expressed in phagocytic cells in the peripheral blood and brain. Activation of FPRL1 is closely related to inflammatory responses in the host defense mechanism and neurodegenerative disorders.ONE-LETTER SEQUENCE: WRWWWWMOLECULAR FORMULA: C61H64N14O7MOLECULAR WEIGHT:1105.3STORAGE CONDITIONS: -20 5C, CAS REGISTRY NUMBER: [878557-55-2], SYNONYMS: WRW4, Formyl Peptide Receptor-Like 1 (FPRL1) Antagonist, H-Trp-Arg-Trp-Trp-Trp-Trp-OHRESEARCH AREA: InflammationREFERENCES: Bae, Y-S. et al. J. Immunol. 173, 607 (2004).; Stenfeldt, Anna-Lena, et al. Inflammation 30.6 (2007): 224-229.; Bj?rkman, Lena, et al. Journal of Leukocyte Biology 83.2 (2008): 245-253.; Lee, Ha Young, et al. The Journal of Immunology 181.6 (2008): 4332-4339.
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