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Medchemexpress LLC WS-383 | 2247544-02-9 | 99.9% | 498.46 g/mol | C18H21Cl2N9S2 | 5MG
Supplier: Medchemexpress LLC HY126075A5MG
WS-383 is a small-molecule, selective, and reversible inhibitor of the DCN1-UBC12 protein-protein interaction. It has a reported IC50 of 11 nM for disrupting DCN1-UBC12 binding, inhibits Cullin3/1 neddylation in cellular assays, and leads to accumulation of p21, p27, and NRF2. Intended for research use in biochemical and cell-based studies.
- Potent DCN1-UBC12 interaction inhibitor (reported IC50 11 nM).
- Selective and reversible mechanism of action.
- Inhibits Cullin3/1 neddylation in cell-based assays.
- Induces accumulation of cell-cycle regulators p21 and p27, and NRF2.
- Supplied in small research pack sizes suitable for assay development.
- High reported purity (99.9%) with recommended storage at 4°C; store in solvent at -80°C for long-term stability.
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