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Enzo Life Sciences XAV939 (5 mg). CAS: 284028-89-3
SDP

Supplier:  Enzo Life Sciences BMLWN1000005

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Potent inhibitor of Tankyrase 1 (IC50=11nM) and Tankyrase 2 (IC50=4nM). Inhibition of tankyrase promotes stabilization of axin resulting in β-catenin degradation and Wnt signalling disruption. Inhibits proliferation of the μ-catenin-dependent colon carcinoma cell line DLD-1. Promotes cardiomyogenic development in mesoderm progenitor cells. Alternative name: 3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one. Purity: ≥98% (HPLC). Solubility: Soluble in DMSO (20 mg/ml). Long Term Storage: Ambient.

Catalog No. 50-201-2357


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