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Cayman Chemical XAV939, 284028-89-3, 5 mg

Supplier: Cayman Chemical 135965

Molecular Formula C14H11F3N2OS, Purity ≥98%, Formula Weight 312.3; A small molecule inhibitor of tankyrase 1 and 2 (IC50 = 11 and 4 nM, respectively); increases the protein levels of the axin-GSK3 complex and promotes the degradation of -catenin; inhibits colony formation of APC-deficient colorectal cancer cells at 0.33 M.
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