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Abcam x E-991 dihydrochloride, KCNQ channel blocker; blocks M current, 50MG
Supplier: Abcam AB12008950MG
MW 449.4 Da, Purity >99%. Potent and selective blocker of KCNQ voltage-gated potassium channels. Blocks M current. (IC₅₀ values are 0.98 μM (M-current), 0.71 μM (KCNQ 2), 0.75 μM (KCNQX 1), >100 μM (Kv1.2) and >43 μM (Kv4.3). Potent pulmonary vasoconstrictor. Cognitive enhancer following oral administration in vivo.
The product is subject to the following: Abcam Restricted Use Statement
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